New approach switches on protein degradation machinery

News The latest chemistry news, including important research advances, business and policy trends, chemical safety practices, career guidance, and more. Read More If cellular protein degradation is like the garbage truck picking up the neighborhood trash, then a new approach takes the brakes off and speeds up trash collection.

Researchers led by Michael Rapé at the University of California, Berkeley, have developed a new strategy for what they call stimulated protein degradation , a cousin of targeted protein degradation (DOI: 10.1126/science.aed2525).